Study on Related Factors of Recurrent Cerebral Infarction

Objective To explore the risk factors for recurrent cerebral infarction. Methods Clinical data of 191 patients with recurrent cerebral infarction and 525 patients with first time cerebral infarction from January 2008 to December 2010 were comparatively analyzed and multivariate unconditional Logistic regression analysis were used to analyze related factors. Results The sex ratio,diabetes,drinking,renal insufficiency,incidence of proteinuria,platelet count,homocysteine(HCY),uric acid,creatinine,C-reactive protein,fasting blood glucose,total cholesterol,triacylglycerol,LDL and HDL showed no statistically significant differences between the two groups(P0.05).Compared with control group,age60,history of cerebral infarction,hypertension,coronary disease,smoking,atrial fibrillation,chronic bronchitis and the incidence of hyperfibrinogenemia in recurrent group showed statistically significant differences(P0.05).Multivariate unconditional logistic regression analysis showed that age60(OR=2.021,95%CI(1.336,3.058),P=0.001),hypertension(OR=1.717,95%CI(1.054,2.796),P=0.030) and hyperfibrinogenemia(OR=1.492,95%CI(1.048,2.123),P=0.026) entered the regression equation. Conclusion Cause of stroke recurrence is multifactorial,age60 years,history of hypertension and hyperfibrinogenemia are the risk factors for cerebral infarction recurrence,so intervention measures on controllable factors should be taken to prevent cerebral infarction recurrence.