Effect of Compound Glycyrrhizin on Hepatic Function and Hepatic Fibrosis of Patients with Chronic Hepatitis B
Yu-ling Tian
Abstract
Yu-ling Tian
Abstract
OBJECTIVE: To study the effect of compound glycyrrhizin on hepatic function and hepatic fibrosis of patients with chronic hepatitis B. METHODS: 33 patients with chronic hepatitis B were injected i.v with 80ml compound glycyrrhizin q.d for 4 weeks. The hepatic function, hepatic fibrosis of patients and the clinic effects before and after treatment were observed. RESULTS: The total effective rates for patients with mild, moderate and severe degrees were 100%, 92.3% and 91.7%, respectively. There were significant differences in alanine aminotransferase, total bilirubin(P0.05)after treatment compared with that before. And significant differences were also noted in type Ⅲ precollagen, hyaluronic acid and laminin(P0.05).CONCLUSON:Compound glycyrrhizin has a significant curative effect on improving hepatic function and hepatic fibro_sis in patients with chronic hepatitis B.
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OBJECTIVE: To study the effect of compound glycyrrhizin on hepatic function and hepatic fibrosis of patients with chronic hepatitis B. METHODS: 33 patients with chronic hepatitis B were injected i.v with 80ml compound glycyrrhizin q.d for 4 weeks. The hepatic function, hepatic fibrosis of patients and the clinic effects before and after treatment were observed. RESULTS: The total effective rates for patients with mild, moderate and severe degrees were 100%, 92.3% and 91.7%, respectively. There were significant differences in alanine aminotransferase, total bilirubin(P0.05)after treatment compared with that before. And significant differences were also noted in type Ⅲ precollagen, hyaluronic acid and laminin(P0.05).CONCLUSON:Compound glycyrrhizin has a significant curative effect on improving hepatic function and hepatic fibro_sis in patients with chronic hepatitis B.
Key concepts: Glycyrrhizin, Hepatic fibrosis, Medicine, Gastroenterology, Hepatic function, Chronic hepatic, Internal medicine, Chronic hepatitis