Distribution and drug resistance of pathogenic bacteria from blood samples in cancer patient

Objective To investigate and analyze the distribution and the drug resistance of pathogenic bacteria isolated from blood samples in cancer patients in the hospital.Methods 3044blood samples were cultivated by Bact/Alert 3Dautomated hemanalysis system,VITEK 2compact automatic analyzer was used for bacterial identification and susceptibility test.Corresponding results were analyzed by WHONET 5.4 software.Results Totally 381strains were isolated from 3044blood samples with positive rate of 12.5%.Gram-positive bacteria account for 56.2%,Gram-negative account for 39.6%and candida strains account for 4.2%.The Escherichia coli were the most common in all bacteria(25.2%),then coagulase negative staphylococcus(23.9%)and Staphylococcus aureus(21.8%).Gram-positive bacteria were sensitive to glycopeptides and linezolid.The Gram-negative bacteria were highly sensitive to imipenem,amikacin and piperacillin/tazobactam.Conclusion The pathogenic bacteria isolated from blood culture are widely distributed.The early detection of the isolated pathogens and the drug resistance analysis are very important in guiding the clinical administration.It suggests that antibiotic should be used rationally so as to reduce the drug resistance of bacteria.