Evaluation on the application of serum indeces in the automatic biochemical analyzer

Objective To assess the reliability of serum appearance indeces in the SYNCHRON CX4 PRO System. Methods The interferent provided by Sysmex Corporation was used as samples to detect serum indeces (icteric index,hemolytic index and lipemic index) in the analyzer. The repeatability and accuracy of the outcomes of the detection were statistically analyzed. Results The within-run frequencies of icteric index,hemolytic index,and lipemic index were 95% and 100%,100% and 100%,and 95% and 95%,respectively; While the between-run frequencies of those indeces were 90% and 95%,95% and 95%,and 90% and 95%,respectively. There was no significant difference between the mean values of total bilirubin and hemoglobin from the experimental detection in the samples with different levels of icteric index and hemolytic index and the mean values provided by the producer of the analyzer(P 0.05). The lipemic index did not differ between the determination by the SYNCHRON CX4 PRO system and the detection via turbidimetry of the microplate reader on 150 samples (P 0.05). Conclusions The repeatability and accuracy of the within-run and between-run of the three serum indeces in the SYNCHRON CX4 PRO system are ideal. The procedure is easy and rapid,and the results are stable and reliable. The serum indeces play an important role in the judgement of the results from the chemical detection.