Effect of “Sheng-ming-yuan” on growth performance,blood physiological,biochemical and immunoglobulin and cytokines indices of Boer goats

An experiment was conducted to investigate the effect of Sheng-ming-yuan on growth performance,blood physiological and biochemical indices of Boer goats.A total of 24 three-month-old male goats were assigned randomly to four groups with 6 replicate and intramuscularly injected with 0 mL(control,groupⅠ),0.5 mL(low-dose-group,group Ⅱ),1.0 mL(middle-dose-group,group Ⅲ),and 2.0 mL(high-dose-group,group Ⅳ)·kg DW.The average daily feed intake,average daily gain,blood physiological and biochemical indices were measured on the day before injection(recorded as 0d) and on 15,30,45 and 60 d after injecting sheng-ming-yuan.Results showed that:(1) compared with the groupⅠ,group Ⅲ had significantly higher(P0.05) growth performance from 0 to 60 days after injection;(2)compared with the groupⅠ,group Ⅲ had significantly higher(P0.05) contents of red blood cell and hemoglobin on 60 d after injection;(3)compared with the groupⅠ,group Ⅲ had significantly lower(P0.05) urea nitrogen content on 45 d and cholesterol content on 60 days after injection.Meanwhile,the basal metabolism and serum glucose content were improved in the three experimental groups;(4)compared with the control group,the experimental groups showed significant or extremly significant difference(P0.05 or P0.01) of the contents of IgG,IgM,IgA;(5)the content of IL-2 in experimental group were higher than control group's,but not sigificant;The content of IL-6 in experimental groups significantly than control group.The results implied that injection of Shengmingyuan could improves the growth performance and metabolism efficiency of glucose,protein and fat of goats and improves the contant of immunoglobulin and cytokines.The optimum injection dosage was 1.0 mL/kg DW.