2010•Chinese Journal of Birth Health & HeredityRequires access

Expression and the clinical significance of the leukemia inhibitory factor and its receptor in preterm placental tissue and decidua tissues

Duan Yu-fen

Abstract

Objective:To study the expression of the leukemia inhibitory factor(LIF) and its receptor(LIFR) in preterm placental tissue and decidua tissues.Methods:Immunohistochemical staining to detect leukemia inhibitory factor(LIF) and its receptor(LIFR) in 30 cases of preterm birth(experimental group),30 cases of artificial abortion(control group) placenta and decidua tissue.Using chi-square test(Chi-Square Test) test LIF,LIFR in preterm and artificial abortion of the expression whether there are differences.Results:The LIF,LIFR in preterm placental tissues positive rates were 6.7% and 10% and in decidual tissues positive rates were 10% and 13.3%.Conclusion:The leukemia inhibitory factor(LIF) and its receptor(LIFR) for the maintenance of late pregnancy remains to be studied further.

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Key concepts: Leukemia inhibitory factor receptor, Decidua, Leukemia inhibitory factor, Placenta, Immunohistochemistry, Pregnancy, Receptor, Leukemia