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Expression of leukemia inhibitory factor gene of decidua from normal pregnant women

Gang Li

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Abstract

Objective: To investigate the expression of leukemia inhibitory factor gene in human first trimester decidua. Methods: By reverse transcription-polymerase chain reacion (RT-PCR), the expression of LIF gene of 36 cases of decidua from human normal pregnancy was detected. Results: All of the decidua specimens had strong LIF gene expression. The level of LIF mRNA expression was 1.314± 0.457. Conclusion: Our findings suggested that the expression of LIF gene might play an important role in the early phase of embryo development and also in the maintenance of pregnancy.

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What this paper is about

Objective: To investigate the expression of leukemia inhibitory factor gene in human first trimester decidua. Methods: By reverse transcription-polymerase chain reacion (RT-PCR), the expression of LIF gene of 36 cases of decidua from human normal pregnancy was detected. Results: All of the decidua specimens had strong LIF gene expression. The level of LIF mRNA expression was 1.314± 0.457. Conclusion: Our findings suggested that the expression of LIF gene might play an important role in the early phase of embryo development and also in the maintenance of pregnancy.

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Available abstract

Objective: To investigate the expression of leukemia inhibitory factor gene in human first trimester decidua. Methods: By reverse transcription-polymerase chain reacion (RT-PCR), the expression of LIF gene of 36 cases of decidua from human normal pregnancy was detected. Results: All of the decidua specimens had strong LIF gene expression. The level of LIF mRNA expression was 1.314± 0.457. Conclusion: Our findings suggested that the expression of LIF gene might play an important role in the early phase of embryo development and also in the maintenance of pregnancy.

Key concepts: Decidua, Leukemia inhibitory factor, Gene expression, Gene, Leukemia inhibitory factor receptor, Pregnancy, Leukemia, Biology

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