2000•PubMedRequires access

[Expression of leukemia inhibitory factor in human decidua].

L Wang, Shi C, Yu Chen

Abstract

OBJECTIVE: To study the expression and localization of leukemia inhibitory factor (LIF) in human first trimester decidual. METHOD: By immunohistochemical analysis and in situ hybridization, the LIF mRNA and protein expression were observed in 16 cases of human decidua. RESULTS: LIF mRNA and protein expressions were observed in all decidual specimens, the glanduar epithelium showed higher LIF expression than in stromal cells. CONCLUSION: Expression of LIF in human decidua may contribute to embryo implantation, maintenance of placental functions and embryonic growth promation.

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Available abstract

Key concepts: Decidua, Leukemia inhibitory factor, In situ hybridization, Stromal cell, Immunohistochemistry, Decidual cells, Leukemia inhibitory factor receptor, Embryo