Research on Antivirus Effect of Dureping Injection in Vitro

Objective:To observe the antivirus effect of Dureping Injection in vitro experiments. Methods:Observing the inhibitive effect of different drug-added ways of Dureping Injection against influenza virus FM1 strain in vitro and its antiviral effective rate at 24h,36h,48h and 72h,which were assayed by crystal violet staining method. Results:Dureping Injection showed an obvious inhibitive effect against adsorption of the virus and inhibition on its prolongation inside MDCK. It was found that Dureping Injection had direct killing effect on the virus at high concentration(≥0.18 mg/mL).Its antiviral effect goes to the peak at 48h after infection, with the prolongation of acting time of drug the inhibitive effect of Dureping Injection kept no change at the high concentration(≥0.27 mg/mL)and weakened at low concentration. Conclusion:Dureping Injection has an obvious effect against influenza virus FM1 strain in vitro.