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2011•Immunological JournalRequires access

Diagnostic value of rSj26-Sj32 in patients with acute schistosomiasis japonicum

Cai ShiFei

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Abstract

We aimed to investigate the diagnostic value of rSj26-Sj32 in acute schistosomiasis japonicum.ELISA,Dot-ELISA and Dipstick were built by the purified rSj26-Sj32 protein and Schistosoma japonicum adult worm antigen(SjAWA) to detected the IgG levels in sera of patients acute schistosomiasis japonicum,while controls were set with the patients with clonorchiasis sinensis,paragonimiasis westermani,alveolar echinococcosis,cystic echinococcosis,hepatitis B,or lung tuberculosis as well as the health donors.As the results,the sensitivity of rSj26-Sj32-ELISA,rSj26-Sj32-Dot-ELISA and rSj26-Sj32-Dipstick were 90.00%,100.00% and 96.00% in diagnosing acute schistosomiasis japonicum,respectively,while the specificity were 97.67%,95.35% and 97.67% respectively.The rSj26-Sj32 antigen shows high sensitivity and specificity for the diagnosis of acute schistosomiasis japonicum,which might be used as a diagnostic antigen for acute schistosomiasis japonicum.

About this research paper

What this paper is about

We aimed to investigate the diagnostic value of rSj26-Sj32 in acute schistosomiasis japonicum.ELISA,Dot-ELISA and Dipstick were built by the purified rSj26-Sj32 protein and Schistosoma japonicum adult worm antigen(SjAWA) to detected the IgG levels in sera of patients acute schistosomiasis japonicum,while controls were set with the patients with clonorchiasis sinensis,paragonimiasis westermani,alveolar echinococcosis,cystic echinococcosis,hepatitis B,or lung tuberculosis as well as the health donors.As the results,the sensitivity of rSj26-Sj32-ELISA,rSj26-Sj32-Dot-ELISA and rSj26-Sj32-Dipstick were 90.00%,100.00% and 96.00% in diagnosing acute schistosomiasis japonicum,respectively,while the specificity were 97.67%,95.35% and 97.67% respectively.The rSj26-Sj32 antigen shows high sensitivity and specificity for the diagnosis of acute schistosomiasis japonicum,which might be used as a diagnostic antigen for acute schistosomiasis japonicum.

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Available abstract

We aimed to investigate the diagnostic value of rSj26-Sj32 in acute schistosomiasis japonicum.ELISA,Dot-ELISA and Dipstick were built by the purified rSj26-Sj32 protein and Schistosoma japonicum adult worm antigen(SjAWA) to detected the IgG levels in sera of patients acute schistosomiasis japonicum,while controls were set with the patients with clonorchiasis sinensis,paragonimiasis westermani,alveolar echinococcosis,cystic echinococcosis,hepatitis B,or lung tuberculosis as well as the health donors.As the results,the sensitivity of rSj26-Sj32-ELISA,rSj26-Sj32-Dot-ELISA and rSj26-Sj32-Dipstick were 90.00%,100.00% and 96.00% in diagnosing acute schistosomiasis japonicum,respectively,while the specificity were 97.67%,95.35% and 97.67% respectively.The rSj26-Sj32 antigen shows high sensitivity and specificity for the diagnosis of acute schistosomiasis japonicum,which might be used as a diagnostic antigen for acute schistosomiasis japonicum.

Key concepts: Schistosoma japonicum, Schistosomiasis, Paragonimiasis, Clonorchiasis, Medicine, Dipstick, Helminthiasis, Antigen

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Diagnostic value of rSj26-Sj32 in patients with acute schistosomiasis japonicum — Research Paper | ScholarLens