2013Chinese Journal of Birth Health & HeredityRequires access

Analysis on intervention in abo incompatible hemolytic disease of the newborn

Huang Zha

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Abstract

Objective: To investigate the clinical significance of intervention in ABO incompatible hemolytic disease of the newborn.Methods: The antibody's titer of 1 341 pregnant women with ABO incompatible were detected in serum.The criteria for applying medication was high antibody's titer(≥1∶ 128).Accompanied by dynamic detection of their antibody's titer.The cases did not accepted medication as Control group.Results: 946 cases were high antibody's titer among 1 341cases(70.54%).There were 792 cases accepted the treatment,and it took effect on 78.16% cases after the treatment.The rate of hemolytic disease of newborns was 55.56% in intervention group,76.62% in control group,and there was no significance of that between the two groups.Conclusion: The rate of hemolytic disease of newborns was high in Nanning.In order to reduce the rate of hemolytic disease of newborn,the antibody's titer should be detected,and the intervention also should be carried out in this area.

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Objective: To investigate the clinical significance of intervention in ABO incompatible hemolytic disease of the newborn.Methods: The antibody's titer of 1 341 pregnant women with ABO incompatible were detected in serum.The criteria for applying medication was high antibody's titer(≥1∶ 128).Accompanied by dynamic detection of their antibody's titer.The cases did not accepted medication as Control group.Results: 946 cases were high antibody's titer among 1 341cases(70.54%).There were 792 cases accepted the treatment,and it took effect on 78.16% cases after the treatment.The rate of hemolytic disease of newborns was 55.56% in intervention group,76.62% in control group,and there was no significance of that between the two groups.Conclusion: The rate of hemolytic disease of newborns was high in Nanning.In order to reduce the rate of hemolytic disease of newborn,the antibody's titer should be detected,and the intervention also should be carried out in this area.

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Available abstract

Objective: To investigate the clinical significance of intervention in ABO incompatible hemolytic disease of the newborn.Methods: The antibody's titer of 1 341 pregnant women with ABO incompatible were detected in serum.The criteria for applying medication was high antibody's titer(≥1∶ 128).Accompanied by dynamic detection of their antibody's titer.The cases did not accepted medication as Control group.Results: 946 cases were high antibody's titer among 1 341cases(70.54%).There were 792 cases accepted the treatment,and it took effect on 78.16% cases after the treatment.The rate of hemolytic disease of newborns was 55.56% in intervention group,76.62% in control group,and there was no significance of that between the two groups.Conclusion: The rate of hemolytic disease of newborns was high in Nanning.In order to reduce the rate of hemolytic disease of newborn,the antibody's titer should be detected,and the intervention also should be carried out in this area.

Key concepts: Titer, ABO blood group system, Medicine, Antibody, Hemolytic disease of the newborn (ABO), Antibody titer, Immunology, Disease

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