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Relationship between ABO hemolytic disease of newborn and maternal antibody

Liqiang Wu

Abstract

Objective To study the relationship between ABO hemolytic disease of newborn and maternal antibody. Methods The titer of blood group antibody in 122 mothers of O blood group during prenatal diagnosis and blood group serology, bilirubin and hemoglobin level of newborn infants were tested with routine methods. The relationship between ABO hemolytic disease of newborn and the titer of blood group antibody was studied. Results The titer of blood group antibody was remarkably related with ABO hemolytic disease of newborn (P0.01),with the descent of hemoglobin (P0.01) and with bilirubin level of newborn within 24 h (P0.01). Conclusion Detecting the titer of maternal blood group antibody can monitor and predict ABO hemolytic disease of newborn infants.

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Key concepts: ABO blood group system, Hemolytic disease of the newborn (ABO), Medicine, Antibody, Immunology, Blood type (non-human), Rh blood group system, Antibody titer