ScholarLens Back to search
2007•Sichuan Mental HealthRequires access

Comparative analysis of fluvoxamine combining with clozapine in the treatment of obsessive-compulsive disorder

Jin Zhum

Open publisher page 0 citations

Abstract

Objective To investigate the efficacy of fluvoxamine combining with clozapine in the treatment of obsessive-compulsive disorder(OCD).Method 45 patients with OCD were randomly treated with fluvoxamine combining with clozapine(n=25) and fluvoxamine only(n=20).The efficacy was measured with Yale-Brown obsessive compulsive scale(Y-BOCS),Hamilton anxiety scale(HAMA)and Hamilton depression scale(HAMD).Results There were significant differences between two groups in overall response showed by the reduction rate of Y-BOCS,HAMA and HAMD total scores.Conclusion It is suggested that fluvoxamine combining with clozapine have a superior effectiveness in the treatment of OCD.

About this research paper

What this paper is about

Objective To investigate the efficacy of fluvoxamine combining with clozapine in the treatment of obsessive-compulsive disorder(OCD).Method 45 patients with OCD were randomly treated with fluvoxamine combining with clozapine(n=25) and fluvoxamine only(n=20).The efficacy was measured with Yale-Brown obsessive compulsive scale(Y-BOCS),Hamilton anxiety scale(HAMA)and Hamilton depression scale(HAMD).Results There were significant differences between two groups in overall response showed by the reduction rate of Y-BOCS,HAMA and HAMD total scores.Conclusion It is suggested that fluvoxamine combining with clozapine have a superior effectiveness in the treatment of OCD.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To investigate the efficacy of fluvoxamine combining with clozapine in the treatment of obsessive-compulsive disorder(OCD).Method 45 patients with OCD were randomly treated with fluvoxamine combining with clozapine(n=25) and fluvoxamine only(n=20).The efficacy was measured with Yale-Brown obsessive compulsive scale(Y-BOCS),Hamilton anxiety scale(HAMA)and Hamilton depression scale(HAMD).Results There were significant differences between two groups in overall response showed by the reduction rate of Y-BOCS,HAMA and HAMD total scores.Conclusion It is suggested that fluvoxamine combining with clozapine have a superior effectiveness in the treatment of OCD.

Key concepts: Fluvoxamine, Hamd, Clozapine, Psychology, Hamilton depression scale, Hamilton Rating Scale for Depression, Anxiety, Obsessive compulsive

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Comparative analysis of fluvoxamine combining with clozapine in the treatment of obsessive-compulsive disorder — Research Paper | ScholarLens