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The effect of carvedilol on chronic heart failure

Han Zhuo

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Abstract

Objective To observe the effect of carvedilor on congestive heart failure disease(CHF). Methods Ninety-two cases of patienets with chronic CHF were randomly divided into two groups: one group was received routine treatment (digitalis, diuretics, vasodilator, ACEI), and another group was received carvedilor (25 mg bid×90 d) as well as routine treatment. Results The treatment efficiency in carvedilor group and control group were respectively 91.3% and 65.2% with signifisent differnce between two groups (P0.01). No adverse reactions associated with carvedilor were observed. The improvements of HR, BP, LVEF, EDV, ESV after treatment in carvedilor group were significant (P0.01 or P0.05). Conclusion Carvedilor with routine therapy may be a safe way to treat CHF.

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What this paper is about

Objective To observe the effect of carvedilor on congestive heart failure disease(CHF). Methods Ninety-two cases of patienets with chronic CHF were randomly divided into two groups: one group was received routine treatment (digitalis, diuretics, vasodilator, ACEI), and another group was received carvedilor (25 mg bid×90 d) as well as routine treatment. Results The treatment efficiency in carvedilor group and control group were respectively 91.3% and 65.2% with signifisent differnce between two groups (P0.01). No adverse reactions associated with carvedilor were observed. The improvements of HR, BP, LVEF, EDV, ESV after treatment in carvedilor group were significant (P0.01 or P0.05). Conclusion Carvedilor with routine therapy may be a safe way to treat CHF.

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Available abstract

Objective To observe the effect of carvedilor on congestive heart failure disease(CHF). Methods Ninety-two cases of patienets with chronic CHF were randomly divided into two groups: one group was received routine treatment (digitalis, diuretics, vasodilator, ACEI), and another group was received carvedilor (25 mg bid×90 d) as well as routine treatment. Results The treatment efficiency in carvedilor group and control group were respectively 91.3% and 65.2% with signifisent differnce between two groups (P0.01). No adverse reactions associated with carvedilor were observed. The improvements of HR, BP, LVEF, EDV, ESV after treatment in carvedilor group were significant (P0.01 or P0.05). Conclusion Carvedilor with routine therapy may be a safe way to treat CHF.

Key concepts: Carvedilol, Medicine, Digitalis, Heart failure, Internal medicine, Ejection fraction, Cardiology, Vasodilation

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