Clinical Treatment Observation of Anti-tuberculosis Drug-induced Liver Damage

Objective To explore clinical treatment of liver damage caused by anti-tuberculosis drugs.Methods Totally 88 cases of anti-tuberculosis drug-induced liver damage patients were randomly divided into the treatment group of 44 cases and the control group of 44 cases.The control group used potassium magnesium aspartate.The treatment group used diammonium glycyrrhizinate combined with reduced glutathione.To observe the change of clinical symptoms and signs and liver function before and after the treatment after 2 weeks.Results The total effective rates in treatment group and control group were respectively 95.5% and 72.7%,the effect of the treatment group was better than that of the control group,there was a significant difference(P0.05).There was significant changes in the liver function of the two groups before and after the treatment,there was significant difference in the comparison between the two groups(P0.01).Liver function recovery of the treatment group after the treatment was better than the control group(P0.05).Conclusion Diammonium glycyrrhizinate combined with reduced glutathione in the treatment of anti-tuberculosis drug-induced liver damage has exactly curative effect,safe and reliable.