Efficacy of Dachaihu and Yinchenhao decoction combined with medicine in patients with acute biliary pancreatitis

Objective To study the efficacy and safety of Dachaihu decoction and Yinchenhao decoction and addition with medicine in patients with acute biliary pancreatitis. Methods A total of 56 patients of acute biliary pancreatitis (ABP) were recruited in the randomized trial. The efficacy and safety of Dachaihu decoction and Yinchenhao decoction and addition with medicine were assessed by symptoms, physical and laboratory examination. Results The efficacy of the treatment group was better than control group and had significant difference, (P0.05). The time of abdominal pain and abdominal bloating relief, and the first defecation time in treatment group were significantly shorten than those of control group, (P0.05). The blood amylase, urine amylase, blood lipase, leukocyte, and C-reactive protein of two groups were all significantly decreased between the two groups. But there were no significant difference between two group after treatment (P0.05). Two case had nausea and vomiting after oral administration of traditional Chinese Medicine and disappeared by enema. Conclusion As a safety and effective combination, Dachaihu and Yinchenhao decoction combined with medicine can remarkably relief symptoms and improve lab index in treating patients with ABP.