Clinical Observation of Xuebijing treating Acute Exacerbation of Chronic Obstructive Pulmonary Diseases

Objective:We observe the efficacy of Xuebijing injection in treating acute exacerbation of chronic obstructive pulmonary diseases(AECOPD).Methods:60 patients with AECOPD were randomly divided into two groups.30 cases were for the treatment group,the other 30 cases for control group.All cases were treated with routine fundamental treatment,and the treatment group were added with Xuebijing injection 50mL in 100mL normal saline intravenous infusion twice per day.Clinical efficacy were evaluated afer 10 days course of treatment.C-reactive protein(CRP) and fibrinogen(FIB),two inflammation maker,were measured and compared.Results:The total effective rate of clinical efficacy was much higher in treatment group than which in control group(P0.05),96.7% and 80.0% for treatment group and control group respectively.There were notable decrease for CRP and FIB in both group,the reduction in treatment group was more prominent than control(P 0.05).Conclusion:Using for adjunctive therapy in AECOP,Xuebijing injection was effective for lessening inflammatory reaction and improving therapeutic effect.