Effect of Xuebijing injection on chronic obstructive pulmonary disease and blood coagulation function

Objective To observe the efficacy Xuebijing injection on patients with chronic obstructive pulmonary disease at acute exacerbation stage (AECOPD) and the impact of the drug on blood coagulation. Methods There 60 patients were randomly divided into control group consisted of 30 cases treated with conventional therapy and treatment group also conssited of 30 cases and with conventional therapy plus Xuebijing 50ml.by intravenous injection 2 times daily. The prothrombin time(PT),thrombin time(TT),activated partial thromboplastin time(APTT),fibrinogen(Fbg) and platelet count (PLT) in the two groups were observed before treatment and a week after treatment. Results The results were significantly different in treatment group after treatment compared to that before treatment (P 0.01). The conditions of patients in treatment group were much improved after treatment compared with those of control group(P0.05). Conclusion Xuebijing injection can improve the conditions of patients with chronic obstructive pulmonary disease at acute exacerbation stage and protect coagulation function of patients.