ScholarLens Back to search
2008•Lishizhen Medicine and Materia Medica ResearchRequires access

Synergy and Attenuation of Cyclophosphamidum(CTX) Activities by LiuJunZi Decoction

Zhi-Qin Liu

Open publisher page 0 citations

Abstract

Objective To observe the synergy and attenuation of cyclophosphamidum(CTX) activities by LiuJunZi Decoction.Methods S180 tumor bearing mice models were established and then divided randomly into four groups,including control group with tumor,CTX group,LiuJunZi Decoction(high and low dose) combined with CTX groups.Each group had 10 mice.After 10 days of treatment,the mice in the four groups were all killed.The effects of LiuJunZi Decoction on tumor weight,immune function and antioxidative enzyme were measured respectively.Results LiuJunZi Decoction could promote spleen lymthocyte proliferation,NK activity and increase tumor-weight-inhibiting rates,activity of SOD,GSH-pX,and decreased the concentration of MDA significantly compared with CTX group(P0.05).Conclusion The synergy and attenuation of LiuJunZi Decoction can be attributed to improve immune function and anti-oxidative capacity.

About this research paper

What this paper is about

Objective To observe the synergy and attenuation of cyclophosphamidum(CTX) activities by LiuJunZi Decoction.Methods S180 tumor bearing mice models were established and then divided randomly into four groups,including control group with tumor,CTX group,LiuJunZi Decoction(high and low dose) combined with CTX groups.Each group had 10 mice.After 10 days of treatment,the mice in the four groups were all killed.The effects of LiuJunZi Decoction on tumor weight,immune function and antioxidative enzyme were measured respectively.Results LiuJunZi Decoction could promote spleen lymthocyte proliferation,NK activity and increase tumor-weight-inhibiting rates,activity of SOD,GSH-pX,and decreased the concentration of MDA significantly compared with CTX group(P0.05).Conclusion The synergy and attenuation of LiuJunZi Decoction can be attributed to improve immune function and anti-oxidative capacity.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective To observe the synergy and attenuation of cyclophosphamidum(CTX) activities by LiuJunZi Decoction.Methods S180 tumor bearing mice models were established and then divided randomly into four groups,including control group with tumor,CTX group,LiuJunZi Decoction(high and low dose) combined with CTX groups.Each group had 10 mice.After 10 days of treatment,the mice in the four groups were all killed.The effects of LiuJunZi Decoction on tumor weight,immune function and antioxidative enzyme were measured respectively.Results LiuJunZi Decoction could promote spleen lymthocyte proliferation,NK activity and increase tumor-weight-inhibiting rates,activity of SOD,GSH-pX,and decreased the concentration of MDA significantly compared with CTX group(P0.05).Conclusion The synergy and attenuation of LiuJunZi Decoction can be attributed to improve immune function and anti-oxidative capacity.

Key concepts: Decoction, Immune system, Spleen, Medicine, Pharmacology, Traditional medicine, Normal group, Internal medicine

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Synergy and Attenuation of Cyclophosphamidum(CTX) Activities by LiuJunZi Decoction — Research Paper | ScholarLens