Diagnostic value of multi-tumor markers protein biochip detection system in breast cancer

Objective:To study the diagnostic value of 12 kinds of tumor markers in protein biochip detection system (C12 detection system for short). Methods: C12 was used to quantitatively detect 12 kinds of tumor markers (CEA,AFP,CA125,CA19-9,NSE,CA242,HCG,HGH,CA15-3,F-PSA,PSA,Ferritin) in the sera of 200 patients with primary breast cancer and 100 healthy women. Results: Of the 22 early-staged breast cancer patients,106 (53%) presented positive tumor marker.Of the 100 healthy women,positive tumor marker was detected in 12 (12%),demonstrating that the sensitivity and specificity for diagnosis of breast cancer were 53% and 88%,respectively,with tumor marker protein biochip. Conclusion: To early breast cancer,the diagnostic value of multi-tumor markers protein biochip detection system (C12 detection system) is limited,it can only be used to enhance the efficiency and accuracy of the tumor detection in clinic.