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DETERMINATION OF RIBAVIRIN IN EYE DROPS BY FIRST ORDER DERIVATIVE SPECTROPHOTOMETRY

Shuang Chen

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Abstract

OBJECTIVE:To improve the methods to determine the contents of ribavirin in ribavirin eye drop METHODS:First order derivative spectrophotometry was used to determined by UV at 222 nm and Δλ 2 nm RESULTS:The average recovery for this method was 99 9%( n=5 ),and the RSD was 0 846% CONCLUSION:The method was simple and accurate,it can be used to determine the contents of ribabirin in eye drops

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What this paper is about

OBJECTIVE:To improve the methods to determine the contents of ribavirin in ribavirin eye drop METHODS:First order derivative spectrophotometry was used to determined by UV at 222 nm and Δλ 2 nm RESULTS:The average recovery for this method was 99 9%( n=5 ),and the RSD was 0 846% CONCLUSION:The method was simple and accurate,it can be used to determine the contents of ribabirin in eye drops

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Available abstract

OBJECTIVE:To improve the methods to determine the contents of ribavirin in ribavirin eye drop METHODS:First order derivative spectrophotometry was used to determined by UV at 222 nm and Δλ 2 nm RESULTS:The average recovery for this method was 99 9%( n=5 ),and the RSD was 0 846% CONCLUSION:The method was simple and accurate,it can be used to determine the contents of ribabirin in eye drops

Key concepts: Ribavirin, Spectrophotometry, Chromatography, Derivative (finance), Second derivative, Drop (telecommunication), Chemistry, Analytical Chemistry (journal)

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