2003•Journal of Pediatric PharmacyRequires access

Determination of content of ribavirin granules by UV

Yong Xu

Abstract

Objective:To establish an UV method for determination of content of ribavirin granules.Methods:The concentration of rib-avirin granules was measured at207nm wavelength which was characteristic absorption peak of ribavirin.Results:The calibration curve was linear within the range of5~25μg/ml.The linear regression equation is A=1.74×10 -2 +0.04631C,r=0.9999(n=5).The average re-covery was99.7%,RSD=0.80%.Conclusion:The method is simple,rapid and accurate.

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Key concepts: Ribavirin, Calibration curve, Content (measure theory), Linear relationship, Content determination, Linear regression, Absorption (acoustics), Calibration