2014Medical Innovation of ChinaRequires access

Effect of Simvastatin Treatment for Elderly Coronary Heart Disease Patients with Hyperlipidemia

Huang Dong-me

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Abstract

Objective: To observe the therapeutic effect and the mechanism of different dose of atorvastatinin treatment of elderly patients with coronary heart disease and hyperlipidemia. Method: 120 cases were divided into observation group and control group, the two groups were treated for infrastructure, control with simvastatin atorvastatin group 60 mg/d on the basis of this, the 1 time/d. The observation group was given simvastatin and atorvastatin 40 mg/d, 1 time/d. To observe changes of blood lipid levels in the two groups. Result: After administration, blood lipid levels of the two groups significantly decreased, the observation group effect was more obvious, with a significant difference between the two groups(P0.05). The observation group's the incidence of adverse reactions was only 15%, which was higher than that of the observation group 66.66%(P0.05). Conclusion: 40 mg in doses of simvastatin is the routine clinical dose is safe and effective for the treatment of coronary heart disease in elderly patients with hyperlipidemia.

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What this paper is about

Objective: To observe the therapeutic effect and the mechanism of different dose of atorvastatinin treatment of elderly patients with coronary heart disease and hyperlipidemia. Method: 120 cases were divided into observation group and control group, the two groups were treated for infrastructure, control with simvastatin atorvastatin group 60 mg/d on the basis of this, the 1 time/d. The observation group was given simvastatin and atorvastatin 40 mg/d, 1 time/d. To observe changes of blood lipid levels in the two groups. Result: After administration, blood lipid levels of the two groups significantly decreased, the observation group effect was more obvious, with a significant difference between the two groups(P0.05). The observation group's the incidence of adverse reactions was only 15%, which was higher than that of the observation group 66.66%(P0.05). Conclusion: 40 mg in doses of simvastatin is the routine clinical dose is safe and effective for the treatment of coronary heart disease in elderly patients with hyperlipidemia.

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Available abstract

Objective: To observe the therapeutic effect and the mechanism of different dose of atorvastatinin treatment of elderly patients with coronary heart disease and hyperlipidemia. Method: 120 cases were divided into observation group and control group, the two groups were treated for infrastructure, control with simvastatin atorvastatin group 60 mg/d on the basis of this, the 1 time/d. The observation group was given simvastatin and atorvastatin 40 mg/d, 1 time/d. To observe changes of blood lipid levels in the two groups. Result: After administration, blood lipid levels of the two groups significantly decreased, the observation group effect was more obvious, with a significant difference between the two groups(P0.05). The observation group's the incidence of adverse reactions was only 15%, which was higher than that of the observation group 66.66%(P0.05). Conclusion: 40 mg in doses of simvastatin is the routine clinical dose is safe and effective for the treatment of coronary heart disease in elderly patients with hyperlipidemia.

Key concepts: Simvastatin, Medicine, Hyperlipidemia, Atorvastatin, Coronary heart disease, Incidence (geometry), Blood lipids, Internal medicine

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