Observation of the curative effect of Stilamin on 30 cases of malignant intestinal ostruction

Objective To investigate the effect of Somatostatin on malignant intestinal obstruction caused by gastrointestinal tumors which is not suitable for operation.Method From January 2008 to December 2100,30 cases of malignant intestinal ostruction were randomly divided into treatment group and control group.The treatment group received routine therapy combined with Somatostatin(6 mg/d) by 24 hours continuous infusion for three to twelve days.The clinical efficacy was observed and compared in both groups.Results The healing effect of the treatment group was significantly higher than that of the control group.The remission rate of abdominal pain and abdominal distention was 80.0% and 53.3% respectively(P0.05).The exhaust of anus was earlier [(93.0% and 60.0%)](P0.01).The average volume of gastroenteral decompression reduced more rapidly [(216±158) ml/d and(522±184) ml/d](P0.001).No fluid-air in the intestinal and in the colon was observed at the 14 patients′ plain abdominal radiography.C reactive protein was significantly different before and after treatment.Life quality was improved significantly.Conclusion On the basis of conventional therapy,Somatostatin is efficient in treatment of malignant intestinal obstruction caused by gastrointestinal tumors.It can improve clinical symptoms and improve life quality.It is worthy of promotion and application.