2009•Zhonghua zhongyiyao xuekanRequires access

Optimization of the Extraction Process of Tianyin Capsule

Manling Ma

Abstract

Objective:To optimize the conditions for alcohol extraction of Tianyin capsules.Methods:The extraction process was studied by orthogonal experimental design as guided by the yield of extract and the content of gastrodin,total flavonoids,ginkgolides as measuring index.Results:The optimal extraction conditions:70℃,and extracted 2 times by 70% ethanol,The time for each extraction was 2.0 hours.The first time used 12 times alcohol,while the second used 8 times alcohol.Conclustion:The extraction procedure is stable and feasible,it could be used for the preparation of Tianyin capsule.

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Key concepts: Gastrodin, Ginkgolides, Extraction (chemistry), Chromatography, Capsule, Yield (engineering), Alcohol, Chemistry