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2004•Chinese journal of integrated traditional and Western medicineRequires access

Clinical Therapy Effects of Shugan Jianpi Ruanjian Mixture on Liver Fibrosis

Yu-Qing Gong

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Abstract

Objective:To explore the therapy effect of treating the chronic hepatitis B with liver fibrosis by Shugan Jianpi Ruanjian Mixture.Methods:Radio Immunoassay was used to observe the parameters of fibrosis level such as hyaluronic acid (HA), laminin (LN) and procollagen of type Ⅲ (PCⅢ). 76 patients with abnormal prameters of fibrosis level were randomly divided into two groups. 38 patients of treatment group treated by Shugan Jianpi Ruanjian Mixture and the compared group treated by Heluo Shugan capsule. The changes of liver function and the parameters of liver fibrosis were observed. Results:The parameters of fibrosis level such as HA, LN, PCⅢ were greatly improved in treatment group than in compared group ( P 0.01), and liver function was improved in treatment group than in compared group ( P 0.05).Conclusion:Shugan Jianpi Ruanjian Mixure for liver fibrosis is useful.

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What this paper is about

Objective:To explore the therapy effect of treating the chronic hepatitis B with liver fibrosis by Shugan Jianpi Ruanjian Mixture.Methods:Radio Immunoassay was used to observe the parameters of fibrosis level such as hyaluronic acid (HA), laminin (LN) and procollagen of type Ⅲ (PCⅢ). 76 patients with abnormal prameters of fibrosis level were randomly divided into two groups. 38 patients of treatment group treated by Shugan Jianpi Ruanjian Mixture and the compared group treated by Heluo Shugan capsule. The changes of liver function and the parameters of liver fibrosis were observed. Results:The parameters of fibrosis level such as HA, LN, PCⅢ were greatly improved in treatment group than in compared group ( P 0.01), and liver function was improved in treatment group than in compared group ( P 0.05).Conclusion:Shugan Jianpi Ruanjian Mixure for liver fibrosis is useful.

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Available abstract

Objective:To explore the therapy effect of treating the chronic hepatitis B with liver fibrosis by Shugan Jianpi Ruanjian Mixture.Methods:Radio Immunoassay was used to observe the parameters of fibrosis level such as hyaluronic acid (HA), laminin (LN) and procollagen of type Ⅲ (PCⅢ). 76 patients with abnormal prameters of fibrosis level were randomly divided into two groups. 38 patients of treatment group treated by Shugan Jianpi Ruanjian Mixture and the compared group treated by Heluo Shugan capsule. The changes of liver function and the parameters of liver fibrosis were observed. Results:The parameters of fibrosis level such as HA, LN, PCⅢ were greatly improved in treatment group than in compared group ( P 0.01), and liver function was improved in treatment group than in compared group ( P 0.05).Conclusion:Shugan Jianpi Ruanjian Mixure for liver fibrosis is useful.

Key concepts: Medicine, Internal medicine, Gastroenterology, Fibrosis, Hyaluronic acid, Procollagen peptidase, Liver fibrosis, Capsule

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