2007•Practical Preventive MedicineRequires access
Effect of Huxinkang on Atherosclerosis Rabbit Induced by High Lipid Diet
Liu Bai-yan
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Abstract
To study the effect of Huxinkang on atherosclerosis rabbit induced by high lipid diet.Methods The models were developed by feeding high cholesterol diet,and Huxinkang was administered by low,middle and high doses respectively.The changes of serum lipid and apoprotein were assessed and analyzed.Results Serum TC,TG and LDL-c were significantly decreased in the middle-and high-dose groups as compared with the model group(P0.05),and the low dose group showed a slight decrease too(P0.05).There was no significant difference in HDL-c between the model group and the others(P0.05).The levels of serum TC,LDLC and TG in the high dose group was significantly lower than those of the low dose group(P0.05),but HDL-c showed no significant difference between them(P0.05).Serum TC and LDLC in the middle dose group were significantly lower as compared with the low dose group(P0.05),but no significant difference was found in HDL-C and TG.There was no significant difference in serum HDL-C,TG,LDL-c and TC between the middle-and high-dose groups(P0.05).Conclusion Huxinkang can decrease serum lipid profiles,and the middle-and high-dose groups are more effective as compared with the low dose group.