2014•Zhongguo yaofangRequires access

Study on Chemical Constituents in Compound Lobelia Chinensis

Le Shi

Abstract

OBJECTIVE:To study the chemical constituents in Compound Lobelia chinensis decoction. METHODS:The compounds were isolated from Compound L. chinensis decoction and purified by TLC,silica gel and gel column chromatography. The structures were elucidated by physicochemical properties and spectral analysis. RESULTS:6 compounds were obtained and elucidated as apigenin-7-O-β-d-glucoside(1),gallic acid(2),luteolin-7-O-β-d-glucoside(3),hesperidin(4),n-butyl-α-d-fructofuranoside(5)and n-butyl-β-d-fructofuranoside(6)by physicochemical properties and spectral analysis. CONCLUSIONS:Compounds 1-6are isolated from Compound L. Chinensis decoction for the first time.

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Key concepts: Chemistry, Gallic acid, Luteolin, Silica gel, Decoction, Spectral analysis, Chromatography, Column chromatography