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Study on expression and significance of CD117 and CD34 in gastrointestinal stromal tumors

Guihong Li

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Abstract

Objective:To study the expressions of CD117 and CD34 of gastrointestinal stromal tumors (GIST) and their clinical significance. Methods: Twenty-two cases of GIST were investigated with clinicopatholgical observation and immunohistochemical analysis of CD117,CD34. Results: The positive rate of CD117 and CD34 of these cases were 100% and 83.3% respectively in GIST. 54.6% cases of GIST originated in stomach, 36.4% cases in small intestine and 9.1% of cases in other places of digestive tract. Conclusion: Expressions of CD117 and CD34 are the special antibodies for diagnosing GIST, and can be used to diagnose the disease.

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What this paper is about

Objective:To study the expressions of CD117 and CD34 of gastrointestinal stromal tumors (GIST) and their clinical significance. Methods: Twenty-two cases of GIST were investigated with clinicopatholgical observation and immunohistochemical analysis of CD117,CD34. Results: The positive rate of CD117 and CD34 of these cases were 100% and 83.3% respectively in GIST. 54.6% cases of GIST originated in stomach, 36.4% cases in small intestine and 9.1% of cases in other places of digestive tract. Conclusion: Expressions of CD117 and CD34 are the special antibodies for diagnosing GIST, and can be used to diagnose the disease.

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Available abstract

Objective:To study the expressions of CD117 and CD34 of gastrointestinal stromal tumors (GIST) and their clinical significance. Methods: Twenty-two cases of GIST were investigated with clinicopatholgical observation and immunohistochemical analysis of CD117,CD34. Results: The positive rate of CD117 and CD34 of these cases were 100% and 83.3% respectively in GIST. 54.6% cases of GIST originated in stomach, 36.4% cases in small intestine and 9.1% of cases in other places of digestive tract. Conclusion: Expressions of CD117 and CD34 are the special antibodies for diagnosing GIST, and can be used to diagnose the disease.

Key concepts: CD117, GiST, CD34, Stromal cell, Medicine, Immunohistochemistry, Stomach, Gastrointestinal tract

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