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ANALYSIS OF IMMUNOHISTOCHEMICAL AND PATHOLOGICAL CHARACTERISTICS OF GASTROINTESTINAL STROMAL TUMORS

Yu HuiLing

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Abstract

Objective:To study the pathological and immunohistochemical characteristics of gastrointestinal stromal tumors(GIST).Methods:48 cases of GIST were analyzed for CD117,CD34,SMA and S-100 express by immunohistochemical SP.Results:Among 48 cases of GIST,89.6% were positive for CD117,83.3% were positive for CD34,31.3% were positive for SMA and 14.6% were positive for S-100.Conclusion:CD117 and CD34 seem to be useful antibodies in the diagnosis of GIST,a high misdiagnosis in GIST can be avoidable by using both CD117 and CD34.

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What this paper is about

Objective:To study the pathological and immunohistochemical characteristics of gastrointestinal stromal tumors(GIST).Methods:48 cases of GIST were analyzed for CD117,CD34,SMA and S-100 express by immunohistochemical SP.Results:Among 48 cases of GIST,89.6% were positive for CD117,83.3% were positive for CD34,31.3% were positive for SMA and 14.6% were positive for S-100.Conclusion:CD117 and CD34 seem to be useful antibodies in the diagnosis of GIST,a high misdiagnosis in GIST can be avoidable by using both CD117 and CD34.

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Available abstract

Objective:To study the pathological and immunohistochemical characteristics of gastrointestinal stromal tumors(GIST).Methods:48 cases of GIST were analyzed for CD117,CD34,SMA and S-100 express by immunohistochemical SP.Results:Among 48 cases of GIST,89.6% were positive for CD117,83.3% were positive for CD34,31.3% were positive for SMA and 14.6% were positive for S-100.Conclusion:CD117 and CD34 seem to be useful antibodies in the diagnosis of GIST,a high misdiagnosis in GIST can be avoidable by using both CD117 and CD34.

Key concepts: GiST, CD117, CD34, Immunohistochemistry, Pathological, Stromal cell, Medicine, SMA*

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