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Pathologic and Immunohistochemical Aanalysis of 24 Cases of Gastrointestinal Stromal Tumor

Lei De-li

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Abstract

Objective To investigate the pathologic and immunohistochemical features of CD117 CD34 SMA S-100 and diagnostic criteria of gastrointestinal stromal tumors(GIST). Methods 24 cases of GIST were studied by routine and immunohistochemistry. Results The GISTS showed two bases cell types spindle and epithelioid; 21 cases, tumor cells of GIST were positivery stained for CD117. 18 cases, tumor cells of GIST were positively stained for CD34. Conclusion GIST which have no evidence of specific differentiation constitute the largest category of mesenchymal tumous of gastointestinal tract.The expression of CD117 and CD34 play an improtant role in the diagnosis of GIST.

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Objective To investigate the pathologic and immunohistochemical features of CD117 CD34 SMA S-100 and diagnostic criteria of gastrointestinal stromal tumors(GIST). Methods 24 cases of GIST were studied by routine and immunohistochemistry. Results The GISTS showed two bases cell types spindle and epithelioid; 21 cases, tumor cells of GIST were positivery stained for CD117. 18 cases, tumor cells of GIST were positively stained for CD34. Conclusion GIST which have no evidence of specific differentiation constitute the largest category of mesenchymal tumous of gastointestinal tract.The expression of CD117 and CD34 play an improtant role in the diagnosis of GIST.

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Available abstract

Objective To investigate the pathologic and immunohistochemical features of CD117 CD34 SMA S-100 and diagnostic criteria of gastrointestinal stromal tumors(GIST). Methods 24 cases of GIST were studied by routine and immunohistochemistry. Results The GISTS showed two bases cell types spindle and epithelioid; 21 cases, tumor cells of GIST were positivery stained for CD117. 18 cases, tumor cells of GIST were positively stained for CD34. Conclusion GIST which have no evidence of specific differentiation constitute the largest category of mesenchymal tumous of gastointestinal tract.The expression of CD117 and CD34 play an improtant role in the diagnosis of GIST.

Key concepts: GiST, CD117, CD34, Immunohistochemistry, Pathology, Stromal cell, Stromal tumor, Gastrointestinal tract

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