Application of amniotic cell kargotyping in the prenatal diagnosis.

Objective:The aim of this study was to make prenatal diagnosis using amniotic cell.Methods:Amniotic cell gotten by amniocentesis were cultured and kargotyped.Results:Cases were cultured successfully in 255 cases.The successful rate was 96.9%.There were 13 cases with chromosomal abnormality cases in 247.Cases who were kargotyped,which take 5.3% of the total cases.Among 13 cases with kargotype disorder,3 cases were autosomal chromosomal abnormalities,2 cases were sex chromosomal abnormalities,3 cases were mosaics,3 cases were balanced translocations and two cases were other chromosomal abnormalities.Conclusion:Amniocentesis and kargotyping are qualified for prenatal diagnosis of fetal chromosomal disease for its safety efficiency and reliability.