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Comparison of insulin analogue combination treatment and insulin pump treatment in newly diagnosed type 2 diabetic patients

XU Meilun

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Abstract

Objective: To observe the effects and the cost of insulin analogue combination treatment and insulin pump treatment in newly diagnosed type 2 diabetic patients with severe hyperglycemia.Methods: 80 newly diagnosed type 2 diabetic patients with severe hyperglycemia were divided into group A and group B in random,with 40 patients in each group.Group A was treated with insulin aspart subcutaneous injections before meals and the insulin glargine subcutaneous injections at bedtime.Group B was treated with continuous subcutaneous insulin infusion and a dose of injection before each meal by insulin pump.The blood glucose,the incidence rate of hypoglycemia,time and cost which spent to make the blood glucose up to the standard,daily insulin doses after treatment were compared.Results: There were no significant difference between two groups in blood glucose,insulin doses,and time when the blood glucose up to the standard after treatment(P0.05),but the cost of group B was obviously higher than that of group A(P0.01).Conclusion: Treatment by insulin aspart and insulin glargine combination in newly diagnosed type 2 diabetic patients has the similar effects to insulin pump therapy,but the former is cheaper.

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Objective: To observe the effects and the cost of insulin analogue combination treatment and insulin pump treatment in newly diagnosed type 2 diabetic patients with severe hyperglycemia.Methods: 80 newly diagnosed type 2 diabetic patients with severe hyperglycemia were divided into group A and group B in random,with 40 patients in each group.Group A was treated with insulin aspart subcutaneous injections before meals and the insulin glargine subcutaneous injections at bedtime.Group B was treated with continuous subcutaneous insulin infusion and a dose of injection before each meal by insulin pump.The blood glucose,the incidence rate of hypoglycemia,time and cost which spent to make the blood glucose up to the standard,daily insulin doses after treatment were compared.Results: There were no significant difference between two groups in blood glucose,insulin doses,and time when the blood glucose up to the standard after treatment(P0.05),but the cost of group B was obviously higher than that of group A(P0.01).Conclusion: Treatment by insulin aspart and insulin glargine combination in newly diagnosed type 2 diabetic patients has the similar effects to insulin pump therapy,but the former is cheaper.

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Available abstract

Objective: To observe the effects and the cost of insulin analogue combination treatment and insulin pump treatment in newly diagnosed type 2 diabetic patients with severe hyperglycemia.Methods: 80 newly diagnosed type 2 diabetic patients with severe hyperglycemia were divided into group A and group B in random,with 40 patients in each group.Group A was treated with insulin aspart subcutaneous injections before meals and the insulin glargine subcutaneous injections at bedtime.Group B was treated with continuous subcutaneous insulin infusion and a dose of injection before each meal by insulin pump.The blood glucose,the incidence rate of hypoglycemia,time and cost which spent to make the blood glucose up to the standard,daily insulin doses after treatment were compared.Results: There were no significant difference between two groups in blood glucose,insulin doses,and time when the blood glucose up to the standard after treatment(P0.05),but the cost of group B was obviously higher than that of group A(P0.01).Conclusion: Treatment by insulin aspart and insulin glargine combination in newly diagnosed type 2 diabetic patients has the similar effects to insulin pump therapy,but the former is cheaper.

Key concepts: Medicine, Insulin aspart, Insulin, Hypoglycemia, Insulin pump, Bedtime, Insulin glargine, Internal medicine

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