Effect of the short-term intensive therapy of insulin analogue combination treatment of newly diagnosed type 2 diabetic patients

Objective To observe the effects and the cost of the combination of insulin glargine with insulin lispro treatment and insulin pump treatment in newly diagnosed type 2 diabetic patients with severe hyperglycemia.Methods 60 newly diagnosed type 2 diabeticpatients with severe hyperglycemia were divided into observation group and control group in random,with 30 patients in each group.The observation group was treated with insulin lispro subcutaneous injections before meals and the insulin glargine subcutaneous injections at bedtime.The control group was treated with continuous subcutaneous insulin infusion and a dose of injection before each meal by insulin pump.The blood glucose,the incidence rate of hypoglycemia,time and cost which spent to make the blood glucose up to the standard,daily insulin doses after treatment were compared.Results Blood glucose in the two groups were significantly decreased,and the difference was significant(P0.01).There were no significant difference between two groups in blood glucose,insulin doses,and time when the blood glucose up to the standard after treatment(P0.05),but the cost of control group was obviously higher than that of observation group(P0.01).Conclusion Treatment by the combination of insulin glargine and insulin lispro in newly diagnosed type 2 diabetic patients has the similar effects to insulin pump therapy,but the money spent is cheaper.