ScholarLens Back to search
2000•Sichuan Journal of Cancer ControlRequires access

Experimental study on the anti-cancer drug sensitivityof cancer cells with MTT colormetric assay

Xiaoming Li

Open publisher page 0 citations

Abstract

Objective:To study the anti-cancer drug sensitivity in cancer cells with MTT colormetric assay.Methods:primary cancer cells from 46 patients (15 gastric cancer,10 lung cancer,12 colon cancer,8 breast cancer) were examined in vitro with MTT assay to find out their drug sensitiviy to 8 routine chemotheraputic drugs.Results:Different cancer cells have different sensitivity to the same chemotherapeutic medicine and each tumor has its own drug-sensitivity table.Conclusion:MTT assay is an easy and quick method for drug sensitivity test in vitro and it provides experimental basis for individual chemotherapy.

About this research paper

What this paper is about

Objective:To study the anti-cancer drug sensitivity in cancer cells with MTT colormetric assay.Methods:primary cancer cells from 46 patients (15 gastric cancer,10 lung cancer,12 colon cancer,8 breast cancer) were examined in vitro with MTT assay to find out their drug sensitiviy to 8 routine chemotheraputic drugs.Results:Different cancer cells have different sensitivity to the same chemotherapeutic medicine and each tumor has its own drug-sensitivity table.Conclusion:MTT assay is an easy and quick method for drug sensitivity test in vitro and it provides experimental basis for individual chemotherapy.

Why it matters

A significance statement is not available in the OpenAlex record.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

Objective:To study the anti-cancer drug sensitivity in cancer cells with MTT colormetric assay.Methods:primary cancer cells from 46 patients (15 gastric cancer,10 lung cancer,12 colon cancer,8 breast cancer) were examined in vitro with MTT assay to find out their drug sensitiviy to 8 routine chemotheraputic drugs.Results:Different cancer cells have different sensitivity to the same chemotherapeutic medicine and each tumor has its own drug-sensitivity table.Conclusion:MTT assay is an easy and quick method for drug sensitivity test in vitro and it provides experimental basis for individual chemotherapy.

Key concepts: Medicine, MTT assay, Cancer, Drug, Lung cancer, Cancer cell, Breast cancer, Pharmacology

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
Experimental study on the anti-cancer drug sensitivityof cancer cells with MTT colormetric assay — Research Paper | ScholarLens