Effects of Jianpi Fuzheng decoction on symptom and immune function in patients with advanced liver cancer

Objective:To observe the influence on the symptom and immune function of advanced primary liver cancer patients treated with Jianpi Fuzheng decoction.Methods:A total of 60 patients were averagely randomized into treatment group and control group,which were all given the same western medical treatment.The treatment group was additionally given Jianpi Fuzheng decoction.A month for a period of treatment,to evaluate the short-term efficacy after two months.Traditional Chinese medicine symptoms,adverse reaction and immune function were observed and compared between the two groups.Results:There was significant difference in the total response rates between the two groups(83.3%,60.0%,P0.05).The two group had a comparison after treatment on function of liver(ALT,AST,TBil),which all improved(P0.05),especially in the aspect of ALT and AST,the treatment group had much more significantly improved(P0.05).The ratio of T-lymphocyte subsets such as CD3+,CD4+,CD4+/CD8+were all increased after treatment(P0.05),while CD8+ decreased(P0.05);comparison between two group showed the difference was statistically significant(P0.05).In contrast,control group after treatment before treatment and comparison,the difference was not statistically significant(P0.05).Comparison of toxic and side effects of the two group showed the effects in the treatment group was significantly lower than the control group(P0.05).Conclusion:Jianpi Fuzheng decoction can relive clinical symptoms,improve immune function,improve quality of life and prolong survival time of patients with advanced primary liver cancer.