2002Chinese Journal of New Drugs and Clinical RemediesRequires access

Intravenous low dose esmolol in treating patients with supraventricular tachyarrythmias

Sheng-Chi Wang

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Abstract

AIM: To observe the efficacy of intravenous low dose esmolol in treating patients with supraventricular tachyarrythmias(SVT). METHODS: A total of thirty patients with STV:including ten patients with sinus tachycardia, seven patients with paroxysmal supraventricular tachycardia, nine patients with atria fibrillation and four patients with flutter [M 17,F 13;age(48± s 15 a) received iv bolus esmolol 3-5 mg, and followed by an intravenous drip 1-3 mg·min -1. The ventricular heart rate and blood pressure, ECG were recorded before and after treatment 1 h of treatment. RESULTS: The heart rate after treatment 1 h was (99±31) beat·min -1 obvious lower than (147±16)beat·min -1 before treatment (P0.01). The total effective rate was 83 %. It was effective for the treatment of the above four types of SVT. Hypotension occurred in only one patient, and resolved within 20 min after discontinuation of esmolol infusion. CONCLUSION: The result of the study indicates that intrarenous low dose esmolol is effective for the treatment of SVT.

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AIM: To observe the efficacy of intravenous low dose esmolol in treating patients with supraventricular tachyarrythmias(SVT). METHODS: A total of thirty patients with STV:including ten patients with sinus tachycardia, seven patients with paroxysmal supraventricular tachycardia, nine patients with atria fibrillation and four patients with flutter [M 17,F 13;age(48± s 15 a) received iv bolus esmolol 3-5 mg, and followed by an intravenous drip 1-3 mg·min -1. The ventricular heart rate and blood pressure, ECG were recorded before and after treatment 1 h of treatment. RESULTS: The heart rate after treatment 1 h was (99±31) beat·min -1 obvious lower than (147±16)beat·min -1 before treatment (P0.01). The total effective rate was 83 %. It was effective for the treatment of the above four types of SVT. Hypotension occurred in only one patient, and resolved within 20 min after discontinuation of esmolol infusion. CONCLUSION: The result of the study indicates that intrarenous low dose esmolol is effective for the treatment of SVT.

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Available abstract

AIM: To observe the efficacy of intravenous low dose esmolol in treating patients with supraventricular tachyarrythmias(SVT). METHODS: A total of thirty patients with STV:including ten patients with sinus tachycardia, seven patients with paroxysmal supraventricular tachycardia, nine patients with atria fibrillation and four patients with flutter [M 17,F 13;age(48± s 15 a) received iv bolus esmolol 3-5 mg, and followed by an intravenous drip 1-3 mg·min -1. The ventricular heart rate and blood pressure, ECG were recorded before and after treatment 1 h of treatment. RESULTS: The heart rate after treatment 1 h was (99±31) beat·min -1 obvious lower than (147±16)beat·min -1 before treatment (P0.01). The total effective rate was 83 %. It was effective for the treatment of the above four types of SVT. Hypotension occurred in only one patient, and resolved within 20 min after discontinuation of esmolol infusion. CONCLUSION: The result of the study indicates that intrarenous low dose esmolol is effective for the treatment of SVT.

Key concepts: Esmolol, Medicine, Supraventricular tachycardia, Heart rate, Anesthesia, Discontinuation, Atrial flutter, Bolus (digestion)

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