Clinical Research on Bozi Ziyin Runchang Decoction for Treatment of 116 Cases of Chronic Functional Constipation

Objective: To study the clinical curative effect of Bozi Ziyin Runchang decoction(BZRD) for treatment chronic functional constipation(CFC) and the influence on the colon transmission function.Method:One hundred and sixteen cases of CFC were randomly divided into treatment group and control group,59 cases and 57 cases respectively.The treatment group was given BZRD,1 agent/daily,the control group was given Maren Runchang soft capsule,8 capsules,bid.Period of treatment was 4 weeks.Symptom of defecation difficult,Bristol score,defecation time,defecation frequency and abdominal distension,and begin colon transmission test were observed.Result: After treatment,the treatment group's symptom defecation difficult was significantly lower than that in control group(P0.01);after the treatment and 4 weeks after treatment,whole colon transmission time in the treatment group was less than that in control group(P0.01);after treatment,the treatment group total effectiveness was 93.22%,which is higher than that of 77.19% in control group(P0.05).After treatment,the two groups of the recurrence rate difference was not obvious.Conclusion: BZRD for treatment of CFC has significant clinical curative effect,good safety,promising clinical application.