Clinical significance of determination of P-selectin and platelet parameters in patients with pneumonia

Objective: To investigate the clinical significance of detection of P-selectin and platelet parameters in the illness evaluation and therapeutic effect of patients with pneumonia.Methods: 126 cases of patients with acute pneumonia in our hospital from January 2008 to December 2010 were divided into severe pneumonia group(42 cases) and mild pneumonia group(84 cases),at the same time,100 cases of healthy persons were chosen as control group.The test results of P-selectin and platelet parameters between the three groups were compared.Results: PLT of patients with acute pneumonia was higher than that of control group with significant difference(P0.01);P-selectin and PLT of severe pneumonia group increased significantly,while PDW,MPV and P-LCR decreased,compared with mild pneumonia group and control group,there were significant differences(P0.01);P-selectin,PDW,MPV and P-LCR of mild pneumonia group had no significant difference compared with control group(P0.05).Conclusion: Abnormal results of platelet parameters and functional status of patients with pneumonia is a common pathological process.The test results of P-selectin,platelet parameters in patients with pneumonia can be used as an important index to valuate the progress of the disease and an index for estimation of the prognosis.