Plasma homocysteine testing and clinical application

Objective To investigate the relationship of plasma homocysteine(hcy) with cardiovascular or cerebrovascular diseases and early renal damage of type 2 diabetes mellitus by detection of plasma homoncysteine.Methods 265 patients aged 4o to 70 with Cardiovascular or cerebrovascular disease and type 2 diabetes mellitus kidney disease as well as 52 cases with physical examination were selected for detecting levels of plasma homocystine by Roche p800.Results After statistical analysis,plasma Hcy levels of cardiovascular disease group,cerebrovascular disease group and type 2 diabetes mellitus kidney disease B group were significantly higher than physical examination group(P0.05).There were no significant difference between Plasma hcy level of type 2 diabetes mellitus kidney disease A group and physical examination group.Conclusion High Hcy level is closely correlated with cardiovascular diseases,it is also an important risk factor.Plasma levels of Hcy are positively correlated with cerebral vascular disease,the concentration of plasma Hcy gradually increases with the occurrence and development of diabetic nephropathy.