2010•China Medical HeraldRequires access

Study on chemosensitivity of breast cancer with MTT assay

Yan Liu

Abstract

Objective:To explore the value of MTT assay in vitro for patients with breast cancer.Methods:Chemosensitivities of ten chemotherapy drugs to cells of the breast cancer were detected by MTT assay.Results:The breast cancer cells were hypersensitive to anticancer drug of PTX,NVB,VP-16,5-FU,DDP;hyposensitive to VCR,ADM,MTX,MMC,HCPT.Conclusion:MTT assay can help to select chemotherapy drugs and compose reasonable individual chemotherapeutic scheme.

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Key concepts: Medicine, MTT assay, Breast cancer, Chemotherapy, Cancer, Oncology, In vitro, Pharmacology