Detection and susceptibility to antibiotics of Mycoplasma in genitourinary tract

Objective To investigate infection statue and antibiotic susceptibility of Mycoplasma urealyticum and Mycoplasma hominis in the genitourinary tract in our area,so as to instruct the rational use of antibiotics. Methods Genitourinary secretions were collected with swabs.They were cultured with the diagnostic kit of Mycoplasma(Biomerieux Company) to detect M urealyticum and M.hominis.Meanwhile the susceptibility of Mycoplasma against 9 antimicrobial agents was tested with the same kit.According to the manual of the kit, the results were read.The data were statistically analyzed.Results A total of 2 410 samples were collected,and the positive rate was 58.1%.Among 1410 positive cases of Mycoplasma,901 cases were M.urealyticum (37.4%),85 were M.hominis(3.5%),and 415 were M urealyticum combined with M.hominis(17.2%). The susceptibility rate of M.urealyticum to josamycin,pristinamycin,ciprofloxacin was 98.8%,98.8%and 6.4%respectively,while the susceptibility rate of M urealyticum combined with M hominis was 86.9%, 86.8%and 2.6%respectively.Conclusion M.urealyticum is the major cause of Mycoplasma infection in genitourinary system.Josamycin and pristinamycin are more effective than other antimicrobial agents to treat Mycoplasma infection.Ciprofloxacin is more resistant than other antimicrobial agents.Sensitive antibiotics should be selected based on the results of bacterial culture and drug sensitivity tests so as to raise the clinical curative effects.