Detection and antibiotic susceptibility of Mycoplasma in genitourinary tract.

Objective To investigate the infection status and antibiotic susceptibility of Ureaplasma urealyticum(Uu) and Mycoplasma hominis(Mh) in the genitourinary tract in our region,so as to provide guidance for rational use of antibiotics.Method Genitourinary secretions were collected with swabs and cultured with the diagnostic kit of Mycoplasma to detect U.urealyticum and M.hominis.Meanwhile the susceptibility of Mycoplasma against 9 antimicrobial agents was tested with the same kit.The data were statistically analyzed.Result Of the total 1210 samples collect,the positive rete was 56.4%.Among 683 positive cases of Mycoplasma,628 cases were U.urealyticum(51.9%),14 cases were M.hominis(1.2%),and 41 cases were U.urealyticum combined with M.hominis(3.4%).The susceptibility rates of U.urealyticum to josamycin,pristinamycin and ofloxacin were 98.5%,97.0% and 1.5% respectively,while those of U.urealyticum combined with M.hominis were 100%,100% and 0.0% respectively.Conclusion U.urealyticum was the major cause of Mycoplasma infection in genitourinary system.Josamycin and pristinamycin were more effective than other antimicrobial agents to treat Mycoplasma infection,while Ofloxacin was less efficient than other antimicrobial agents.Sensitive antibiotics should be selected based on the results of bacterial culture and drug sensitivity tests so as to raise the clinical curative effects.