2012Anti-infection PharmacyRequires access

Analysis of Drug Sensitivity and Detection of Mycoplasma of 1652 Patients with Genitourinary Tract Infection

Feng Li

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Abstract

Objective: To analyze the anti-microbial susceptibility and detection of Mycoplasma of patients with genitourinary tract infection in 2009 in Suzhou No.5 people's hospital and to provide a basis for the rational use of drugs for clinical treatment .Methods: Biomerieux IST kit was used for identification and susceptibility testing of the Mycoplasma strains.Results: Specimens positive rate was 30.93% in 1 652 patients with Mycoplasma. Of the Mycoplasma detected, Ureaplasma urealyticum(Uu) was alone 82%, Mycoplasma huminis(Mh) was 1.37%, and Uu+Mh was indentified in 16.63%.The results of anti-microbial susceptibility testing showed that the Mycoplasma isolates were the most susceptible to pristinamycin, doxycycline, josamycin and tetracycline: 100%, 97.24%, 95.75% and 90.83% respectively. Ciprofloxacin and ofloxacin were the most susceptible and the sensitive rate of the Mycoplasma to ciprofloxacin and ofloxacin was 10.54% and 9.67% separately. Conclusion: Pristinamycin, doxycycline, josamycin and tetracycline can be used in the treatment of genitourinary tract infections caused by Mycoplasma. The Mycoplasma isolates must be screened for the potential trend of resistance for guiding rational anti-microbial therapy.

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Objective: To analyze the anti-microbial susceptibility and detection of Mycoplasma of patients with genitourinary tract infection in 2009 in Suzhou No.5 people's hospital and to provide a basis for the rational use of drugs for clinical treatment .Methods: Biomerieux IST kit was used for identification and susceptibility testing of the Mycoplasma strains.Results: Specimens positive rate was 30.93% in 1 652 patients with Mycoplasma. Of the Mycoplasma detected, Ureaplasma urealyticum(Uu) was alone 82%, Mycoplasma huminis(Mh) was 1.37%, and Uu+Mh was indentified in 16.63%.The results of anti-microbial susceptibility testing showed that the Mycoplasma isolates were the most susceptible to pristinamycin, doxycycline, josamycin and tetracycline: 100%, 97.24%, 95.75% and 90.83% respectively. Ciprofloxacin and ofloxacin were the most susceptible and the sensitive rate of the Mycoplasma to ciprofloxacin and ofloxacin was 10.54% and 9.67% separately. Conclusion: Pristinamycin, doxycycline, josamycin and tetracycline can be used in the treatment of genitourinary tract infections caused by Mycoplasma. The Mycoplasma isolates must be screened for the potential trend of resistance for guiding rational anti-microbial therapy.

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Available abstract

Objective: To analyze the anti-microbial susceptibility and detection of Mycoplasma of patients with genitourinary tract infection in 2009 in Suzhou No.5 people's hospital and to provide a basis for the rational use of drugs for clinical treatment .Methods: Biomerieux IST kit was used for identification and susceptibility testing of the Mycoplasma strains.Results: Specimens positive rate was 30.93% in 1 652 patients with Mycoplasma. Of the Mycoplasma detected, Ureaplasma urealyticum(Uu) was alone 82%, Mycoplasma huminis(Mh) was 1.37%, and Uu+Mh was indentified in 16.63%.The results of anti-microbial susceptibility testing showed that the Mycoplasma isolates were the most susceptible to pristinamycin, doxycycline, josamycin and tetracycline: 100%, 97.24%, 95.75% and 90.83% respectively. Ciprofloxacin and ofloxacin were the most susceptible and the sensitive rate of the Mycoplasma to ciprofloxacin and ofloxacin was 10.54% and 9.67% separately. Conclusion: Pristinamycin, doxycycline, josamycin and tetracycline can be used in the treatment of genitourinary tract infections caused by Mycoplasma. The Mycoplasma isolates must be screened for the potential trend of resistance for guiding rational anti-microbial therapy.

Key concepts: Josamycin, Mycoplasma, Ofloxacin, Doxycycline, Ureaplasma urealyticum, Microbiology, Ciprofloxacin, Genitourinary system

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Analysis of Drug Sensitivity and Detection of Mycoplasma of 1652 Patients with Genitourinary Tract Infection — Research Paper | ScholarLens