Ureaplasma urealyticuminfections in genital tract of female patients and analysis of drug resistance

OBJECTIVE To approach the current status of Ureaplasma urealyticum(Uu)infections in the genital tract of the female patients and analyze the drug resistance so as to provide the scientific evidence for the clinical treatment.METHODS Mycoplasma IST kits(bioMerieux,France)was used for the Mycoplasma culture,counting,identification and drug susceptibility testing.RESULTS The positive rate of Mycoplasma culture for the female patients with nongonococcal urethritis was 52.0%.The positive rate of Uu was 88.9%.The susceptibility rates of Uu to pristinamycin,and doxycycline were the highest,which were more than 90.0%;the Uu was highly sensitive to tetracycline,josamycin and clarithromycin,the drug susceptibility rates were 83.1%,82.1%,and 76.0%,respectively;the drug susceptibility rates to azithromycin and erythromycin were 24.3% and 35.2%,respectively.However,the drug resistance rates of Uu to such quinolones antibiotics as ofloxacin(81.1%)and ciprofloxacin(90.8%)were the highest.CONCLUSIONThe clinicians should focus on the Mycoplasma culture for the female patients with non-gonococcal urethritis and the drug susceptibility testing,which plays an important role in the clinical diagnosis and the reasonable use of antibiotics.