Clinical comparative study on ELISA and TPPA detectioned of treponema pallidum

Objective To observe the effect of enzyme-linked immunosorbent assay(ELISA) and gelatin treponema pallidum particle agglutination test(TPPA) for detection of treponema pallidum.Methods 283 cases serum samples respectively did ELISA and TPPA,and analyzed the results.Results In 158 cases different patients and detection of normal human serum,ELISA and TPPA were not detected in positive law.The serum of 125 cases healthy used ELISA method,syphilis antibody positive rate was 10.4%(13 cases);Used TPPA method,syphilis antibody positive rate was 8.8%(11 cases),the difference was not statistically significant(P0.05),the total coincidence rate was 98.4%.Conclusion ELISA method to the syphilis have a higher sensitivity and specificity and easy standardization,standardization,and suitable for screening large sample;TPPA method,while the sensitivity and specificity are high,but relatively speaking,the operation is more complicated,time-consuming,high cost,suitable for confirmatory test.