Characteristics of ambulatory blood pressure in advanced aged patients with senile hypertension

Objective To investigate the characteristics of 24-hour ambulatory blood pressure in advanced aged hypertensive patients aged over 80 years old.Methods All patients were divided into 3 groups according to their ages,including the advanced aged group (aged≥80,n=88),aged control group (aged from 60 to 79,n=80) and middle-aged control group (aged60,n=25).The parameters and incidence of abnormal circadian rhythm of ambulatory blood pressure,and the incidence of diastolic pressure below 60 mmHg (1 mm Hg=0.133 kPa) were analysed retrospectively in the patients of three groups during antihypertensive treatment.Results The difference of drug administration was not significant statistically (P0.05) among three groups.The difference of average systolic pressure among the whole day,daytime and night was not significant statistically.The average diastolic pressure was lower in the advanced aged group than that in the aged control group or middle-aged control group (all P0.01).The difference average of pulse pressure among the whole day,daytime and night was higher in the advanced aged group than that in the aged control group or middle-aged control group (all P0.01).The incidence of abnormal circadian rhythm of 24-hour ambulatory blood pressure was higher significantly in the advanced aged group than that in the aged control group or middle-aged control group (all P0.05).The incidence of diastolic pressure below 60 mm Hg was higher significantly in the advanced aged group than that in the aged control group and middle-aged control group (all P0.01).Conclusion The advanced aged patients with senile hypertension will have too lower diastolic pressure and abnormal circadian rhythm of blood pressure during the antihypertensive treatment.