ScholarLens Back to search
1999•PubMedRequires access

[A study on relationship between hypertension and polymorphism of ACE gene in male Yi people in Liangshan Yi autonomous prefecture, Sichuan].

Guangliang Shan, X Wang, Qiu C, Chao Ren, Huijun Li, P Wang, Wu Zhang, Shao-Qiong Liao, Li X, Shirley F. Tong, K Zhang

Open publisher page 2 citations

Abstract

OBJECTIVE: To explore relationship between polymorphism of ACE gene and hypertension. METHODS: A cross-sectional study was conducted and PCR technique was used to analyze gene polymorphism. RESULTS: Genotypes DD, ID and II of ACE gene accounted for 13.0% and 9.7%, 50.9% and 48.4%, and 36.1% and 41.9%, respectively, in the normotensives and hypertensives. Frequencies of I and D alleles for ACE gene were 61.6% and 66.1%, and 38.4% and 33.9%, respectively, in the normotensives and hypertensives. There was no significant difference in distribution of II, ID and DD genotypes and I/D allele frequencies of ACE gene between the hypertensives and normotensives in male Yi people. CONCLUSION: Association between polymorphism of ACE gene and hypertension was uncertain.

About this research paper

What this paper is about

OBJECTIVE: To explore relationship between polymorphism of ACE gene and hypertension. METHODS: A cross-sectional study was conducted and PCR technique was used to analyze gene polymorphism. RESULTS: Genotypes DD, ID and II of ACE gene accounted for 13.0% and 9.7%, 50.9% and 48.4%, and 36.1% and 41.9%, respectively, in the normotensives and hypertensives. Frequencies of I and D alleles for ACE gene were 61.6% and 66.1%, and 38.4% and 33.9%, respectively, in the normotensives and hypertensives. There was no significant difference in distribution of II, ID and DD genotypes and I/D allele frequencies of ACE gene between the hypertensives and normotensives in male Yi people. CONCLUSION: Association between polymorphism of ACE gene and hypertension was uncertain.

Why it matters

OpenAlex reports 2 citations for this work. Citation counts describe recorded attention and do not establish research quality.

Key contribution

A contribution statement is not available in the OpenAlex record.

Method / approach

Method details are not available in the OpenAlex metadata.

Main findings

Findings are not separately available in the OpenAlex metadata.

Limitations

Limitations are not available in the OpenAlex metadata.

Applications

Application details are not available in the OpenAlex metadata.

Available abstract

OBJECTIVE: To explore relationship between polymorphism of ACE gene and hypertension. METHODS: A cross-sectional study was conducted and PCR technique was used to analyze gene polymorphism. RESULTS: Genotypes DD, ID and II of ACE gene accounted for 13.0% and 9.7%, 50.9% and 48.4%, and 36.1% and 41.9%, respectively, in the normotensives and hypertensives. Frequencies of I and D alleles for ACE gene were 61.6% and 66.1%, and 38.4% and 33.9%, respectively, in the normotensives and hypertensives. There was no significant difference in distribution of II, ID and DD genotypes and I/D allele frequencies of ACE gene between the hypertensives and normotensives in male Yi people. CONCLUSION: Association between polymorphism of ACE gene and hypertension was uncertain.

Key concepts: Genotype, Allele, Polymorphism (computer science), Gene, Genetics, Internal medicine, Gene polymorphism, Allele frequency

Related papers

Related paper 1Related paper 2Related paper 3
Back to paper searchBrowse research topicsOriginal source
[A study on relationship between hypertension and polymorphism of ACE gene in male Yi people in Liangshan Yi autonomous prefecture, Sichuan]. — Research Paper | ScholarLens