Preliminary evaluation of quantitative laboratory method for estradiol(E2) in DXI800 photometric analyzer with EP10-A

Objective:To preliminary evaluation of quantitative laboratory method of DXI800 photometric analyzer with EP10-A.Methods: According to the NCCLS Document EP10-A and Chinese public health profession standard Preliminary Assessment of Quantitation Clinic Analysis Method(WS/T228-2002),collected blood sample of patients and detected E2 continuously for five days with a certain order in the DXI800 analyzer,then calculated deviation,total imprecision,intercept,slope rate,nonlinearity,cross-contamination,drift and carried out statistical analysis.Results: It showed that bias are 1.34 pmo/L,-7.90 pmo/L,9.53 pmo/L,total imprecision are 5.15%,3.79%,7.36% and intercept,slope rate,nonlinearity,cross-contamination,drift were 19.042 pmo/L(P0.01),0.946(P0.01),-0.627(P0.01),0.12(P0.01),-2.226(P0.01)respectively.Conclusion: The deviation,total imprecision,intercept,slope rate,nonlinearity,cross-contamination,drift of the DXI800 analyzer were within permission limit,so the analyzer could satisfy the clinical application and scientific research request of E2.