2014•Chinese Journal of Birth Health & HeredityRequires access
Investigate the significance of prenatal diagnosis indication by the diagnosis of amniotic cell chromosomal abnormalities
Pan Qian-yin
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Abstract
Objective:To assess the prenatal diagnosis indication by the diagnosis of amniotic cell chromosomal abnormalities.Methods:939 specimens(16~24 weeks) of amniotic cell gotten by amniocentesis were cultured and karyotyped.Results:Of the 123 cases,abnormal karyotypes were identified in 54 cases.13 cases were trisomy of human chromosome 21,1 case was trisomy of human chromosome 18,1 case was trisomy of human chromosome 13,9 cases were sexual chromosome abnormalities,14 cases were chromosomal abnormality in balanced translocation,16 cases were other abnormal karyotypes.Conclusion:The diagnosis of fetal chromosomal abnormalities through the test of amniotic cell chromosomal abnormalities is safe and effective.This method is important and worthy of further promotion.